Fatigue is something that we all face after a strenuous, stressful day. It is a feeling when you are more tired than usual (without any apparent reason). But, what if you are always fatigued, or have been experiencing extreme tiredness for long periods? It is nothing except chronic fatigue. Even after getting a full 8-hour sleep, it is like waking up slack, exhausted, confused and demotivated – ugh!

Chronic fatigue presents symptoms like brain fog, lack of energy, poor cognitive abilities that do not go away with sleep. It is very common in individuals suffering from autoimmune conditions, such as, rheumatoid arthritis (RA).

In this blog, we will walk you through six main reasons why a person having RA falls in the high-risk group of chronic fatigue development. These underlying factors may work individually or in unison, prompting you to visit a private GP. Read below for details.

1. Inflammation

Scientists are still conducting their research on the connection between RA-induced inflammation and fatigue. Well, several evidences suggest that inflammation is directly to elevated levels of C-reactive protein and high erythrocyte sedimentation rate (ESR). Some experts even state that fatigue and inflammation are independent, with possible indications of yet-to-be discovered inflammation markers.

2. Joint pain

Many health experts claim joint pain to be the main cause for RA-induced fatigue. Joint pain and fatigue go hand in hand, and they can be present even if blood test (indicating inflammation) reports come normal. Well, fatigue can also happen without any significant pain in the joints. But, if extreme tiredness persists even after successful treatment, visiting a doctor becomes necessary.

3. Sleep apnoea

Individuals with rheumatoid arthritis are more likely to experience sleep apnoea than those who do not have it (up to 75% and more). Sleep apnoea is a disorder in which a person’s breathing constantly stops and starts while he is asleep. This affects how much oxygen the body is able to take in, and can leave you with a feeling of exhaustion, even after you have slept the whole night.  

However, the positive news is – sleep apnoea is treatable (with proper diagnosis and medications). The treatment usually involves utilising a continuous positive airway pressure (CPAP) machine – a device that enhances oxygen intake during sleep. In certain cases, sleep apnoea may not even seem to relate with the symptoms of rheumatoid arthritis. For such scenarios, fatigue may persist even if the RA signs are in proper control.

4. Mental health issues

Mental health issues occur more to individuals having rheumatoid arthritis. They are often seen to cope with symptoms like depression, anxiety, lethargy and mental confusion. This is also backed up by several research studies – most of them say that stress, anxiety and mood aberrations have a direct connection to RA-associated fatigue. Although the exact mechanism is not clear, it is possible that people already struggling with depression and anxiety are more likely to face difficulty in sleeping. In addition to this, there may be effects of anti-depressant medicines and anti-anxiety drugs; causing drowsiness. Well, research is still going on in this particular topic.

5. Anaemia

Most researchers are suggesting that around 70% of individuals suffering from rheumatoid arthritis face anaemic conditions. Anaemia is a blood disorder characterised by extremely low red blood cell count and iron levels. A handful of reasons may be responsible for anaemia. For example, nutritional deficiencies (caused due to poor eating habits and low intake of iron-rich foods), existing chronic metabolic disorders (like diabetes), usage of certain medicines, etc.

6. Medication side effects

While medications serve to treating rheumatoid arthritis, it may cause extreme fatigue. Some medicines like methotrexate trigger fatigue and can even increase the risks for depression, overall body weakness, sleep disturbances (or insomnia), etc. You can visit a private GP – they will assess your condition in detail and incorporate a combination of medications to counteract fatigue.

Treatment for Rheumatoid Arthritis Triggering Fatigue

1. Controlling Inflammation: The primary treatment goal is to reduce inflammation. Disease-modifying antirheumatic drugs (DMARDs) such as methotrexate, or biologic agents like TNF inhibitors, help control the immune system’s over activity. When inflammation is well-managed, fatigue often improves significantly.
2. Addressing Pain and Sleep: Effective pain control using NSAIDs, corticosteroids (for short-term use), or other analgesics can reduce fatigue by improving sleep and daily function. Sleep quality is crucial; hence, sleep disorders like insomnia or sleep apnoea must be timely identified and treated.
3. Lifestyle Modifications: Doing moderate exercise, such as, walking, swimming, yoga regularly can boost energy levels, improve joint mobility, and reduce fatigue. A balanced diet rich in anti-inflammatory foods—like omega-3 fatty acids, fruits, and vegetables—can also help.
4. Psychological Support: Depression and anxiety, common in chronic illness, can worsen fatigue. Cognitive-behavioural therapy (CBT), stress management techniques, and support groups may provide emotional relief and improve energy levels.
5. Medication Review: Some RA medications can contribute to fatigue. Your rheumatologist may adjust doses or switch medications if fatigue becomes unmanageable.

   Lastly, treating RA-related fatigue involves a personalised plan that combines medical, physical, and psychological strategies. Close collaboration with local healthcare providers is prime to achieving optimal outcomes.

Conclusion

In addition to the causes mentioned above, there are a bunch of other factors in contributing to RA-induced fatigue. For example, deficiency of micronutrients (like Vitamin B12 and D), thyroid problems, and chronic infections. You must determine the exact cause of this by consulting a reputed and experienced doctor. However, this is not as easy as it seems. You must have a clear discussion about your current symptoms and how do they affect your life – this will help the physician assess your issue in detail. In turn, he can offer you necessary guidelines and advice to alleviate the symptoms. Several private clinics in South Kensington offer reliable and affordable services for diagnosis, disease management, prevention and more. Remember, the prompter you are in taking the initial step, higher are your chances of obtaining the best care and treatment – see a private GP in South Kensington today.

• Meta Title: Rheumatoid Arthritis Triggering Chronic Fatigue: Everything You Need to Know
• Meta Description: Learn how rheumatoid arthritis can lead to chronic fatigue. Understand the symptoms, triggers, and expert-backed tips to manage both conditions effectively. Read more now!
• Meta Tags: arthritis, chronic fatigue, private GP

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